The Indian Institute of Technology (IIT), Roorkee has actually created a method to handle the after-effects of biomedical grade implants and reduce the possibilities of bacterial infections in joint replacement treatments. Almost 10 percent of bone implants result in failures due to diseases, which call for high doses of medication, according to researchers.
This technique will modify the surface area of metallic implants and load it with an antibacterial drug, which is released gradually over a period of one week or more at the implant website to avoid infections.
Lead scientist Debrupa Lahiri commented, “Our surface-modified implant is an unique method that addresses localised and long-term drug release for locations that are vulnerable to post-surgical infections which often arise throughout joint replacement procedures. The customized implant surface serves for both drug delivery and bone combination.
By using the plasma spray strategy, a 200- micron thick layer of hydroxyapatite (HA) was covered on a titanium metal alloy sheet. HA is biocompatible material with a bone-like mineral structure and used in ceramic implants.
The group discovered that the polymer-HA combination had actually an added benefit, enhancing the impact resistance of the implant by 42 percent. The scientists include teacher Partha Roy at IIT Roorkee and professor Arvind Agarwal at Florida International University, USA along with their respective groups. The other scientists associated with the job are Manoj Kumar R and Kanike Rajesh.